Results of independent validation

• Origin of 132 included articles

textbooks Total

+ -

+

Search 35 79 113

filter

- 7 12 19

Total 45 87 132

• Sensitivities of search strategies:

Toxicology textbooks: 34% (45/132)

search filter: 86% (113/132)

search filter +drug effects (DE-new term)95% (125/132)

Validation set

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