Internal Medicine Journal Club |
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University of Texas Health Science Center |
--> School of Medicine --> | Department of Medicine |
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| Home | Appraising
evidence (levels of evidence & glossaries) |
Applying
evidence (calculators & converters) |
Finding evidence | Keeping up | List of questions |
Before starting
Open http://clinical.uthscsa.edu/
Case
62 year old white male with cirrhosis due to alcohol.
Clinical Question:
Should you screen for hepatocellular carcinoma?
Step I:
Please go to UpToDate and find the answer. Write down what you find and where you find it for group discussion.
Please go to PIER and find the answer (note that it is in two places).Write down what you find and where you find it for group discussion.
Citations:
From PIER and UpToDate:
Bolondi L et al. Surveillance programme of cirrhotic patients
for early diagnosis and treatment of hepatocellular carcinoma: a cost effectiveness
analysis. Gut. 2001;48:251-9.
PMID: 11156649
McMahon BJ, Bulkow L, Harpster A, Snowball M, Lanier A, Sacco F, et al. Screening for hepatocellular carcinoma in Alaska natives infected with chronic hepatitis B: a 16-year population-based study. Hepatology. 2000;32:842-6. PMID: 11003632
From Cochrane:
Sherman M, Peltekian K, Lee C. Screening for hepatocellular carcinoma in chronic carriers of hepatitis B virus: incidence and prevalence of hepatocellular carcinoma in a North American urban population. Hepatology 1995;22:432-8. PMID: 7543434
Yang B, Zhang B, Tang Z. Randomized controlled prospective study of secondary prevention for primary liver cancer. [Article in Chinese], National Medical Journal of China (Zhonghua Yi Xue Za Zhi) 1999;79(12):887-9. PMID: 11715499
