Internal Medicine Journal Club

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Journal Club - 2007-01-16

Numeracy

Diagnosing Adrenal Insufficiency in Severe Sepsis

PMID: 16973979 - DOI (full text): 10.1164/rccm.200509-1369OC

Do their results, especially about baseline values, agree with the NEJM, UpToDate, and PIER?

NEJM algorythm - UpToDate - PIER

Correction of Anemia with Epoetin Alfa in Chronic Kidney Disease

What is the number needed to harm?

PMID: 17108343 - DOI (full text): 10.1056/NEJMoa065485

Survival of patients with stage I lung cancer detected on CT screening

What is the number needed to screen?

PMID: 17065637 - DOI (full text): 10.1056/NEJMoa060476

Relevance of Thyroid Nodules Found Incidentally on CT

What proportion of incidental nodules are malignant? What size cutoff is senstive for malignancy? Is the proportion with malignancy high enough to merit investigation?

PMID: 17056928 - DOI (full text): 10.2214/AJR.05.0468

JWatch.org

PIER - UpToDate

Lymphocyte–White Blood Cell Count Ratio: A Quickly Available Screening Tool to Differentiate Acute Purulent Tonsillitis From Glandular Fever [e.g. mono]

What is the positive predictive value?

PMID: 16973979 - DOI (full text): 10.1164/rccm.200509-1369OC