Journal Club - 2006-11-07

ARS - Clinical Calculator

1. How Do I Perform a Lumbar Puncture and Analyze the Results to Diagnose Bacterial Meningitis? Sharon E. Straus, Kevin E. Thorpe, and Jayna Holroyd-Leduc JAMA. 2006;296:2012-2022. PMID: 17062865 Full text
   • Interventions to reduce headache
     • Choose either atraumatic needles, reinsertion of the stylet, immmobilization, hydration
   • Diagnosis
     • Primer on likelihood ratios
       • Using the calculator above, use prevalence of 50% and try
         • positive OR of 10
         • negative LR of 0.1
     • Table 2. Studies Assessing Cerebrospinal Fluid Analysis in Patients With Suspected Central Nervous System Infection
     • Table 4. Accuracy of Cerebrospinal Fluid Biochemical Analysis in Patients With Suspected Bacterial Meningitis
       • What is pretest probability
       • Lannigan. Fulltext
       • Lindquist. PMID: 3137038
       • Briem. PMID: 6648372
       • Komorowski. Fulltext